Joined: 12/6/2011
Posts: 3326
|
From Alzheimer's Daily News:
(Source: Medical Xpress) - Slowing or preventing the development of Alzheimer's may be as simple as ensuring a brain protein's sugar levels are maintained.
That's the conclusion seven researchers, including David Vocadlo, Canada Research Chair in Chemical Glycobiology. They describe how they've used an inhibitor (Thiamet-G) to stop O-GlcNAcase, a naturally occurring enzyme, from depleting the protein Tau of sugar molecules.
"This work shows targeting the enzyme O-GlcNAcase with inhibitors is a new potential approach to treating Alzheimer's," said Vocadlo. "This is vital since to date there are no treatments to slow its progression.
Go to full story: http://www.physorg.com
|