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Drug For Alzheimer's, Parkinson's and MS Shows Promise
Posted: Wednesday, July 25, 2012 11:34 PM
Joined: 12/6/2011
Posts: 3326

From Alzheimer's Daily News:

(Source: Medical News Today) - A new class of drugs that targets a particular type of brain inflammation is showing early promise for the treatment of Alzheimer's disease, Parkinson's disease, multiple sclerosis and traumatic brain injury.

A pre-clinical study shows one of the drugs stopped mice bred to have Alzheimer's from developing the full-blown disease.


The new class of drugs approaches the treatment of Alzheimer's differently to the ones currently being tested to prevent beta amyloid plaques in the brain. While the plaques are known to indicate Alzheimer's, nobody has yet proved that they cause the disease.


The new class of drugs, known as MW151 and MW189, target a particular type of brain inflammation that is a common denominator in MS, Alzheimer's and Parkinsons, and also in traumatic brain injury and stroke.


More and more scientists are coming round to the idea that inflammation plays a major role in the progressive damage that characterizes these chronic neurological diseases and brain injuries.


In a pre-clinical study researchers report that when MW-151 is given to a mouse genetically engineered to develop Alzheimer's, it stops progression to the full-blown disease.


The results suggest giving the drug before Alzheimer's symptoms are readily apparent may be a promising therapeutic strategy.


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Posted: Friday, July 27, 2012 10:31 AM
Joined: 3/28/2012
Posts: 13

After reading about this, I did a search on Bing with the key words "cytokines" and "anatabine".  I know the target is "inflammation", but I haven't found out if the mechanism is thought to be the same.  However, anatabine is available right now, if it works.