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Non-drug treatments
JackX
Posted: Tuesday, March 7, 2017 6:22 PM
Joined: 12/20/2016
Posts: 100


In the following I list three types of non-drug treatments. It is not complete, a lot of other treatments also exist, such as acupuncture, other alternative medicines, etc.

1) Infrared, or Near Infrared light therapies.

One line of light therapies is pioneered by Michael Hamblin, a Harvard Professor. He, along with Vielight, tested and produced a line of light therapy products, included are

Viewlight 808; Vielight Neuro; Vielight Neuro Alpha, and Vielight Neuro Gamma.

http://vielight.com/devices/

Their test results were reported in 

http://vielight.com/wp-content/uploads/2017/01/Vielight-Pilot-Study-Final-Publication-Dec-2016.pdf

Second line of near infrared light therapy was pioneered in an article

"Turning On Lights to Stop Neurodegeneration: The Potential of Near Infrared Light Therapy in Alzheimer's and Parkinson's Disease"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707222/

Or you can watch here:

https://www.youtube.com/watch?v=b1tK4oe9lmI

This line of research is still at the stage of "proof of concept"

2. NeuroAD from NeuroNix

http://www.neuronixmedical.com/

This is a very interest development. It has been approved in UK, France, etc

The test results is reported in:

http://www.hk-tms.com/download/NeuroAd.pdf

Currently there are several clinical trials using NeuroAD in the US. A listing of the trial sites can be found at:

http://www.neuronixmedical.com/clinical-trials/

If this device passes the FDA and used in the US, the price tag could be pretty (in UK six weeks of therapy cost 6,000 British Pounds.)

3. NeuroEM

A light weight wearable device. 

http://neuroem.com/home/

 

 


JackX
Posted: Friday, May 19, 2017 12:28 PM
Joined: 12/20/2016
Posts: 100


Update on NeuroAD:

Most recent trial on NeuroAD, provides some results not very encouraging:

https://www.scientificamerican.com/article/could-magnetic-brain-stimulation-help-people-with-alzheimer-rsquo-s/

However, the scientists / researchers involved are apparently know more about what they are doing!!

 


HowDoYouDeal
Posted: Wednesday, April 3, 2019 11:47 AM
Joined: 2/17/2019
Posts: 380


results are in, it works, see my other post.

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568598/table/T4/?reportbjectonly

 

Table 4.

Quality of Life and Functional Changes from Baseline, During 12-Week Treatment Period, and After 4-Week No-Treatment Follow-Up Period, Reported By Participant and Families

Patient no. Baseline 12-week treatment period No-treatment follow-up period 1 Apprehensive, spoke predominantly Portuguese with family, complained “her head felt too heavy to hold up, headache.” Only responded to questions. Family stated she was more anxious, had decreased ability to cook or clean, less interactive with family. Openly smiling, laughing, hugged assessor. Stated frequently, head feels “lighter” “clearer,” no headache. Family stated, “more talkative and active” (i.e., cooking, cleaning, going for walks, answering phone). Able to give a recipe to assessor by memory. Progressively more withdrawn, less engaged. More tired, feeling “cloudy” “heavy head,” headaches returned. Cooked and cleaned less, personal hygiene declined. Did not want to participate in family gatherings. 2 Infrequent eye contact with assessor. Predominantly answered in Italian (native language) with long pauses between questions. Stooped posture, shuffling gait, live-in caregiver, assisted with mobility, dressing, personal hygiene, incontinent 6/7 nights. Not initiating conversation, minimal engagement during family visits. Did not discuss his wife's death. Looked directly at assessor, spoke predom-inantly English, humorous, and smiling. Remembered assessor's name, reason for visit and stated, “doing better.” By week 6, walked into office more upright, at steady pace, independently transferred from chairs. Incontinent 1–2/7 nights. Occasionally dressed independently, more communicative, happier with caregiver and family. Acknowledged wife's death and able to speak to family. First week without PBM treatment, rapidly declined in behavior (uncooperative and belligerent); functional decline (required assistance with mobility, hygiene, and dressing); and cognitive decline (less able to follow conversation, respond appropriately, or remember events). Family requested to have LED treatment resumed. 3 Humor was used to compensate for inability to answer questions. Denied memory loss. Thought he was still working. Read and listened to news. Wife not sure what he remembered. Minimal discussion of news or events. Patient stated, “easier to answer test questions,” recognized when unable. Wife stated he was more interactive and was reading his professional publications. Week 10, foot ulcer returned, below-the-knee edema, erythema, pain, grimaced with transfers from chair, and less bright and interactive. Patient treated at foot clinic, little change. Had foot pain all of the time, leg edema below the knee. Less focused during testing, decreased interaction, less humorous, and personal hygiene declined (e.g., not clean shaven). 4 Used to be outgoing, humorous, but then felt less happy. Agreed when wife stated that he was becoming more forgetful (i.e., only drove on familiar routes and misplaced items). Asked wife for test answers. Working part-time, cooks his own ethnic meals. Returned to building “found object sculptures.” Able to re-route driving to accommodate traffic, becoming less forgetful, needed fewer reminders. Less dependent on wife for “entertainment,” generally happier. Looked less to the wife for test answers, laughed, then answered independently. No decline during “No Treatment” period. Wife confirmed husband had not lost the gains achieved during treatment. 5 Patient open about loss of memory and diagnosis of AD. Interactive, but slightly reserved. Aware when unable to answer test questions, needed prompting to provide answer. Stated he and his wife continue to live a full life, but the future was scary. Week 3, stated he felt brighter, world had more color, forgot less frequently as to why he went into a room. Worked in garden with wife, preparing to start oil painting again. More humorous, interactive, less hesitant during testing. Wife (nurse) stated she was pleased with positive changes. Gradual decrease in “brightness and clarity.” Both patient and wife noticed decline in memory, focus, less able to initiate and complete tasks independently.

AD, Alzheimer's disease.