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Photobiomodulation for Alzheimer's Disease: Has the Light Dawned?
Lane Simonian
Posted: Tuesday, July 9, 2019 10:25 AM
Joined: 12/12/2011
Posts: 4599


This is the latest and one of the best articles for the use of light to treat Alzheimer's disease.

https://www.mdpi.com/2304-6732/6/3/77/htm

One key sentence from the article makes me think that there is something there.

Specifically, PBM could reduce peroxynitrite, while still preserving the positive effects of other isoforms of NO synthase, such as endothelial nitric oxygen synthase (eNOS), which is the species primarily responsible for the vasodilating effects of PBM.

Nearly all the problems of Alzheimer's disease can be traced to peroxynitrite: initial inflammation, mitochondrial dysfunction, decreased blood flow, lack of regeneration of neurons and synapses in the hippocampus, and the death of neurons and according to the article, photobiomodulation has been shown to ameliorate these problems.

One of the best Alzheimer's quotes is the following:

[Clinical trials with over-the-counter supplements have concentrated either on items which suppress inflammation, or on antioxidants which scavenge oxygen derived free radicals. Most of these items have proved to be worthless in the treatment of Alzheimer's disease. Similarly most drugs used to treat Alzheimer's disease do little to slow the deterioration, but instead offer a mild temporary symptom relief. However, evidence has been accumulating that the primary driver of Alzheimer's disease is a nitrogen derived free radical called peroxynitrite, which may mediate both amyloid and tau accumulation as well as their toxicity. Excellent results have been obtained with peroxynitrite scavengers, with reversals of Alzheimer's disease in human clinical trials being repeatedly demonstrated. IMHO, the only thing which may be preventing the abolition of Alzheimer's disease is the mental inertia of scientists, as well as the bureaucrats who fund them. Unfortunately, most bureaucrats keep throwing money into repeatedly testing discredited interventions, while ignoring successful ones. Common sense is anything but...] 

The level of current evidence for various peroxynitrite scavengers varies, but it is possible that panax ginseng, aromatherapy, CBD oil, and photobiomodulation can all be used to treat Alzheimer's disease.


Cathyde
Posted: Wednesday, July 10, 2019 9:31 AM
Joined: 4/21/2019
Posts: 30


hello thank you for posting the info I will check u of  m