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New Discovery Closes in on Genetic Link Between Alzheimer's and Diabetes
Myriam
Posted: Tuesday, June 19, 2012 7:29 PM
Joined: 12/6/2011
Posts: 3326


From Alzheimer's Daily News:


(Source: Genetics Society of America) - Scientists from City College of New York report a new spin to our understanding of the relationship between Alzheimer's disease and diabetes, which could point to a therapeutic target for both diseases. The researchers show that a gene in the worm Caenorhabditis elegans, which is similar to a human gene correlated with Alzheimer's disease, is involved in multiple metabolic pathways, including the insulin pathway.


"Mutations in three genes, including the amyloid precursor protein (APP) gene, have been correlated with the inherited form of Alzheimer's disease in humans," said Chris Li, PhD. "Because the equivalent gene we're studying in the model organism C. elegans is involved in many metabolic pathways, it suggests that the human version of the gene likely also plays a role - not only in Alzheimer's disease, but in diabetes as well," Li added.

 

Go to full story: http://www.eurekalert.org