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Hormone Shots Aid Cognition in Older Adults
Posted: Wednesday, August 8, 2012 10:22 PM
Joined: 12/6/2011
Posts: 3326

From Alzheimer's Daily News:

(Source: MedPage Today) - Daily shots of growth hormone-releasing hormone (GHRH) improved cognition in both healthy adults and those with mild cognitive impairment, researchers reported.

In a five-month trial, GHRH was associated with a significant improvement in cognitive performance compared with placebo, according to Laura Baker, PhD, of the University of Washington School of Medicine, and colleagues.


The benefit was driven by significantly better executive function and a trend toward better verbal memory, although visual memory was not changed, the group reported.


GHRH stimulates release of growth hormone from the pituitary, in a pulsatile fashion, which in turn causes the release of insulin-like growth factor 1 from the liver. All three "have potent effects on brain function, their levels decrease with advancing age, and they likely play a role in the pathogenesis of Alzheimer's disease," the researchers wrote.


Evidence suggests that elevating hormone levels in people at risk for cognitive impairment might prevent mental decline or improve function, they noted.


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