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Anxiety Drug Use May Boost Dementia Risk
Posted: Friday, September 28, 2012 9:06 PM
Joined: 12/6/2011
Posts: 3326

From Alzheimer's Daily News:


(Source: MedPage Today) - A French study has found that older patients who used benzodiazepine anti-anxiety drugs were at substantially higher risk of developing dementia.

Earlier studies examining the drugs yielded conflicting results: some found an increased risk of cognitive impairment or dementia, whereas others detected no relationship or even a protective effect.

Billioti de Gage and colleagues analyzed data from the PAQUID cohort study, in which a total of 3,777 people in southwestern France were followed for up to 20 years starting in the late 1980s, with clinic visits every 2 to 3 years.

The scientists calculated an odds ratio of 1.60 for incident dementia after study year 5 associated with new benzodiazepine use.

Those who had ever used benzodiazepines in this analysis were more likely to develop dementia after the 8-year mark. This value was virtually identical for those whose benzodiazepine use was recent and for those whose use was earlier in the past. However, there were not very many recent benzodiazepine users and the increase in dementia risk did not reach statistical significance.

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