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Diabetes Drug May Help Fight Alzheimer's
Posted: Friday, December 14, 2012 1:07 PM
Joined: 12/6/2011
Posts: 3326

(Source: - A drug originally meant to treat diabetes may restore memory in brain cells affected by Alzheimer's disease. Study leader Jack Jhamandas demonstrated that a diabetes drug that never made it to market, known as AC253, could block the toxic effects of amyloid protein that lead to brain-cell death. When the drug AC253 was given to brain cells with Alzheimer's and the shock memory tests were redone, memory was restored to levels similar to those in normal cells.

"This is very important because it tells us that drugs like this might be able to restore memory, even after Alzheimer's disease may have set in," Jhamandas said in a statement. He said their research tests would take a least a year to complete. He noted it is difficult for AC253 to cross the brain barrier, so research teams in pharmaceutical companies would need to design a similar drug that can penetrate brain cells more easily.


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