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NeuroAd
Hopenow
Posted: Sunday, August 7, 2016 9:28 PM
Joined: 12/17/2015
Posts: 32


Does anyone have information on the benefits of using NeuroAd, transcranial magnetic stimulation?  It is being used in Europe and Israel with positive results for improving cognitive function according to the company which has created the device.  The device has been submitted for FDA approval.  Is this all hype or is it real?
Lane Simonian
Posted: Monday, August 8, 2016 9:38 AM
Joined: 12/12/2011
Posts: 5001


The initial clinical trial results were positive for cognition, but more studies would be helpful.

Repetitive transcranial magnetic stimulation combined with cognitive training is a safe and effective modality for the treatment of Alzheimer’s disease: a randomized, double-blind study

 

Cortical excitability can be modulated using repetitive transcranial magnetic stimulation (rTMS). Previously, we showed that rTMS combined with cognitive training (rTMS-COG) has positive results in Alzheimer’s disease (AD). The goal of this randomized double-blind, controlled study was to examine the safety and efficacy of rTMS-COG in AD. Fifteen AD patients received 1-h daily rTMS-COG or sham treatment (seven treated, eight placebo), five sessions/week for 6 weeks, followed by biweekly sessions for 3 months. The primary outcome was improvement of the cognitive score. The secondary outcome included improvement in the Clinical Global Impression of Change (CGIC) and Neuropsychiatric Inventory (NPI). There was an improvement in the average ADAS-cog score of 3.76 points after 6 weeks in the treatment group compared to 0.47 in the placebo group and 3.52 points after 4.5 months of treatment, compared to worsening of 0.38 in the placebo (P = 0.04 and P = 0.05, respectively). There was also an improvement in the average CGIC score of 3.57 (after 6 weeks) and 3.67 points (after 4.5 months), compared to 4.25 and 4.29 in the placebo group (mild worsening) (P = 0.05 andP = 0.05, respectively). NPI improved non-significantly. In summary, the NeuroAD system offers a novel, safe and effective therapy for improving cognitive function in AD.


Serenoa
Posted: Tuesday, August 9, 2016 5:37 AM
Joined: 4/24/2012
Posts: 484


I always ask myself how a specific therapy might be addressing the cause of the disease. In this case, how could magnetic fields affect the pathology of AD? I'm pretty sure that a LACK of magnetic stimulation is not the cause of AD. Therefore, this therapy is not correcting any kind of deficiency that might have lead to the disease. On the other hand, one of the known pathogenic factors of AD is the abnormal accumulation of iron in the brain. Iron can be toxic as an oxidative agent, and it is also associated with amyloid plaques. Magnetic stimulation could be affecting this iron accumulation in some way, and so I wouldn't quickly dissmiss this therapy as quackery.
Eden Desjardins
Posted: Wednesday, October 5, 2016 2:16 PM
Joined: 5/25/2015
Posts: 48


I think magnetic stimulation therapy seems to be promising. I forgot the exact mechanisms but I talked with several exhibitors during a dementia conference who promote this form of therapy. They told me they were within a certain phase for FDA approval.

Funnily enough, there's something called the Vielight Neuro as well, which uses high-powered NIR photons instead of magnetic power. The Neuro seems to be very promising, as well (and I've personally had good experiences with it with my hubby). 


Lane Simonian
Posted: Sunday, October 9, 2016 10:18 AM
Joined: 12/12/2011
Posts: 5001


It is good to now that there are promising treatments out there and that the Neuro is helping your husband.
Hopenow
Posted: Friday, October 28, 2016 8:32 PM
Joined: 12/17/2015
Posts: 32


Hi

Could you post more information on Neuro ? What changes have you noticed in your husband? How long has he been treated by this device?  Any information would be highly appreciated. 


JackX
Posted: Thursday, December 29, 2016 10:41 AM
Joined: 12/20/2016
Posts: 100


The following is the link to the report of Neuro (LLLT)

http://www.prnewswire.com/news-releases/canadian-company-gives-hope-to-alzheimers-sufferers-with-wearable-low-level-light-therapy-300295886.html

It contains a video clip.

Have not seen the official publication report on the results yet. 

Transcranial magnetic stimulation (TMS) involves the use of very short pulsed magnetic fields to stimulate nerve cells in the brain. Since the late 1990s, physicians have used TMS to treat Major Depressive Disorder in adult patients who have failed to achieve satisfactory improvement from antidepressant medications.

  • TMS Therapy is proven and well-tolerated
  • TMS Therapy is a non-drug, non-systemic alternative antidepressant
  • TMS Therapy is an outpatient procedure that takes less than an hour
  • TMS Therapy has no negative effects on memory or ability to concentrate.

 


JackX
Posted: Friday, December 30, 2016 6:44 PM
Joined: 12/20/2016
Posts: 100


This is just in:

"Positive Results for neuroAD Device in Mild Alzheimer's"

http://www.medscape.com/viewarticle/873886

 


JackX
Posted: Wednesday, January 4, 2017 4:40 PM
Joined: 12/20/2016
Posts: 100


Another report on the neuroAD trial results. Little more detailed.

http://finance.yahoo.com/news/neuronix-reports-positive-results-multi-140000497.html

It seems the current round of efforts are all meant to "halt" the disease, not reverse it, let alone "cure" it. As some specialist said, maybe there will never be a "cure".

Of course, that is just from one school of thought.

 


JackX
Posted: Friday, February 10, 2017 9:07 PM
Joined: 12/20/2016
Posts: 100


Most recent reports on NeuroAD:

report on trials results from the U.K.

http://www.express.co.uk/life-style/health/764838/alzheimers-news-magnetic-brain-training-technique-drugs

In addition, there is a Ad from the NeuroAD's maker which shows quite impressive results:

http://www.hk-tms.com/download/NeuroAd.pdf

 

 


Hopenow
Posted: Sunday, February 19, 2017 9:13 PM
Joined: 12/17/2015
Posts: 32


I originally posted about NeuroAd. Are you or a relative suffering from the disease. If so are you considering doing the treatment with   NeuroAd?