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Clinical trial in Canada
Larrytherunner
Posted: Saturday, February 3, 2018 5:53 AM
Joined: 2/26/2016
Posts: 215


I have some more info on the upcoming clinical trial in Canada for the anti-inflammatory drug montelukast (Singulair) for Alzheimer's. Selection is scheduled to begin in March for mild to moderate Alzheimer's patients. The trial will be supervised by Health Canada, which is Canada's version of the FDA. It is registered on ClinicalTrials.gov. You can click on the clinical trials number within the article below to go directly to ClinicalTrials.gov and get more info on the trial.

 

This is not an experimental drug. It was approved in 1998 for long term use for the prevention of asthma attacks. The patent has expired so it is now available in generic. 

 

This is not a repurposed cancer drug or a biologic, so it is not going to cost tens of thousands of dollars a year. A generic 10 mg tablet costs about 50 cents each. Hopefully we will get feedback about the trial in 6 to 10 months. 

 

Lane, please don't add any long scientific sounding post or promotion for Chinese herbs. Thanks.

https://globenewswire.com/news-release/2018/01/24/1304269/0/en/IntelGenx-Initiates-Phase-2A-Montelukast-Versafilm-Clinical-Trial-in-Alzheimer-s-Patients.html

https://clinicaltrials.gov/ct2/show/NCT03402503


Lane Simonian
Posted: Saturday, February 3, 2018 10:48 AM
Joined: 12/12/2011
Posts: 4813


No need for the admonishment this time.  I was just going to thank you for the update.
Larrytherunner
Posted: Saturday, February 3, 2018 12:07 PM
Joined: 2/26/2016
Posts: 215


Thanks Lane for the support.
BadMoonRising
Posted: Saturday, February 3, 2018 9:06 PM
Joined: 4/22/2017
Posts: 321


Larry,

Coincidentally, I read the linked article this morning and immediately thought of you. This was one study I would have liked to join 


Larrytherunner
Posted: Sunday, February 4, 2018 1:40 AM
Joined: 2/26/2016
Posts: 215


BadMoonRising. One reason it would be a good trial to join is that it was found safe by the FDA for long term use. But having to travel all the way to Canada might be a problem.
Lane Simonian
Posted: Monday, February 5, 2018 10:08 AM
Joined: 12/12/2011
Posts: 4813


Certainly, Larry.
Donr
Posted: Monday, March 26, 2018 4:41 AM
Joined: 4/6/2014
Posts: 494


I am a believer.

Don

 


Pawpawsgirl43
Posted: Monday, March 26, 2018 10:45 PM
Joined: 3/26/2018
Posts: 2


Noticed your reply on a post I made. I’m new at this app any helpful advice on getting into the real fat groups and all? I feel overwhelmed with all the info and care taking for my Pawpaw. Pretty much placing my life on hold because I want to do whatever for him. My Pawpaw gave up so much for me I love him more than words can say. He was my world and the dementia diagnosis literally broke me into. Nothing has hurt worse to me this man was my everything and for the longest I was just lost and broken. Hurts so much to see this cruel disease taking over. I would take it from him in s heartbeat if possible.
Lane Simonian
Posted: Sunday, April 1, 2018 11:03 AM
Joined: 12/12/2011
Posts: 4813


This is a good place to come to learn about possible treatments for Alzheimer's disease, but it is one of the least frequented forums on this board.  The best place to post for the most responses is on the caregivers forum.  This is a very tough disease, but there may be ways to lessen its impact.  Best wishes to you and to your pa.  
wolfewoman
Posted: Monday, April 2, 2018 5:40 PM
Joined: 1/1/2018
Posts: 204


Lane, do u have links re Chinese herbs???

I would love to read it.


Larrytherunner
Posted: Monday, June 11, 2018 6:01 AM
Joined: 2/26/2016
Posts: 215


In my original post I made reference to a website article about the clinical trials in Canada. I have just noticed that the website, which was free, has switch to paid subscription, so here is some other info on the trials.

https://globenewswire.com/news-release/2018/01/24/1304269/0/en/IntelGenx-Initiates-Phase-2A-Montelukast-Versafilm-Clinical-Trial-in-Alzheimer-s-Patients.html

https://clinicaltrials.gov/ct2/show/NCT03402503


ethanscott
Posted: Wednesday, June 13, 2018 5:53 AM
Joined: 6/13/2018
Posts: 3


How is this turning out to be?

It's been over 4 months since this was posted

Any updates?


Larrytherunner
Posted: Wednesday, June 13, 2018 7:11 AM
Joined: 2/26/2016
Posts: 215


I have no updates except they seem to be running a couple of months behind schedule. Sometimes you can get the inside scoop by checking the Yahoo investors' blog for Intelgenx. You can get both useful and suspect information there. Clinical trials are not supposed to give out info until they reach a certain point, but sometimes info leaks out.

https://ca.finance.yahoo.com/quote/IGX.V/community/