RSS Feed Print
Possible cause for Alzhiemer's and traumatic brain injury discovered
MissHer
Posted: Friday, September 28, 2018 8:21 AM
Joined: 11/13/2014
Posts: 2342


https://www.sciencedaily.com/releases/2018/09/180926140717.htm
Lane Simonian
Posted: Friday, September 28, 2018 10:24 PM
Joined: 12/12/2011
Posts: 4813


Thank you for continuing to post valuable information here MissHer.  I found a rather complicated, but important explanation as to why the oxidation/nitration of potassium channels is a critical factor in Alzheimer's disease.

Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain

Oxidative modification of the voltage-gated potassium (K+) channel KCNB1 promotes apoptosis in the neurons of cortex and hippocampus through a signaling pathway mediated by Src tyrosine kinases.