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Biogen looking for 1000 volunteers for drug that slows ALZ
alz+
Posted: Saturday, April 18, 2015 6:20 PM
Joined: 9/12/2013
Posts: 3561


http://www.alzheimers.net/4-15-15-promising-new-alzheimers-treatment/


Alzheimer’s Treatment Exceeding Expectations in Early Trials

A new drug from Biogen Idec, a biotechnology firm, has surpassed expectations in early drug trials by slowing seemingly unstoppable cognitive decline. The drug, known as either BIIB037 or aducanumab, works to slow cognitive decline by reducing the amyloid plaques in the brains of people with dementia. Many researchers believe these plaques and tangles of beta amyloid actually cause the neurodegenerative disease.

The first study completed on the drug involved 166 participants and allowed researchers to evaluate dosage requirements and to evaluate the need for further studies on the drug. Researchers used PET imaging and found that the drug did help to remove amyloid from the brain. Participants who took the placebo had unchanged levels of plaque whereas patients who received the highest dose of the drug had a statistically significant reduction in brain plaque.

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