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Alzheimer's Drug Add-On Brings Some Memory Improvement
Posted: Tuesday, March 12, 2013 2:21 PM
Joined: 12/6/2011
Posts: 3326

(Source: LA Times) - In patients with moderate Alzheimer's disease, an experimental drug that alters the brain's "fight or flight" impulse succeeded in improving memory modestly when it was added to at least one of the medications already in wide use to treat the memory-robbing disease.

Compared with subjects taking the drug memantine and a placebo, subjects supplementing their customary drug regimen for three months with the experimental drug--ORM-12741--scored more highly on two measures of memory. One of those tested the quality of patients' memory overall; the other tested the quality of patients' "episodic memory"--the ability to recall events and experiences from one's own past.

Available drugs to treat Alzheimer's disease have only moderate effects on the symptoms of the disease but have never been found to halt or reverse the steady progression of Alzheimer's. Researchers are exploring a wide range of approaches to find drugs that could do that but have so far come up empty.

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