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frontal temperol dementia (FTD)
Posted: Monday, January 9, 2012 8:16 AM
Joined: 11/29/2011
Posts: 182

I'll start this topic as FTD has a lot of it's own issues. It is a rare form of Dementia.


Copied from www.alz.org 


Frontotemporal Dementia (FTD)

Key features

  • FTD is a group of rare disorders in which neurodegeneration chiefly affects brain areas called the frontal and temporal lobes. No single underlying pathological process is known.

  • FTD types are placed in one of two basic clinical groups:

    o The first group is defined by behavioral and personality changes that may include uncharacteristic impulsiveness and lack of inhibition; rudeness or tactlessness; poor financial judgment; inappropriate social conduct, sometimes extending into illegal activities; declining interest in grooming and hygiene; and overeating and weight gain. Individuals typically lack insight into such changes. This group of FTDs includes the well-known Pick’s disease.

    o The second group is characterized by progressive disruption in verbal and written expression (primary progressive aphasia) or naming and understanding meaning (semantic dementia). Memory and other cognitive functions remain relatively unaffected.

  • FTD is rare in general clinical practice.

  • It tends to occur earlier than Alzheimer’s, primarily between ages 35 and 75. Due to its earlier onset and prominent behavioral and personality symptoms, it may be mistaken for a primary psychiatric disorder.

  • Most individuals with FTD perform poorly on neuropsychiatric tests of executive function.

  • Brain imaging often shows damage to the anterior temporal and frontal lobes. If present, this atrophy may be diagnostic.  Distinguishing FTD from Alzheimer’s is the only indication for which Medicare may cover a PET scan for evaluation of dementia.


No treatments are approved by the FDA for frontotemporal dementia, and none have been shown to be effective.

Pathological substrate

No specific abnormality is associated with all cases of frontotemporal dementia. An alternate term for FTD is “dementia lacking distinct histopathologic features.”



Posted: Monday, January 9, 2012 1:10 PM
Joined: 11/29/2011
Posts: 182

also from www.alz.org 


Frontotemporal lobar degeneration 



Includes dementias such as behavioral variant FTLD (bvFTD), primary progressive aphasia, Pick's disease and progressive supranuclear palsy.

Symptoms: Typical symptoms include changes in personality and behavior and difficulty with language. Nerve cells in the front and side regions of the brain are especially affected. No distinguishing microscopic abnormality is linked to all cases.

Brain changes: The brain changes of bvFTD may be present at the same time as the brain changes of Alzheimer's, but people with bvFTD generally develop symptoms at a younger age (at about age 60) and survive for fewer years than those with Alzheimer's.

Learn more about frontotemporal dementia.

Jim Knox
Posted: Monday, January 16, 2012 6:03 AM
Joined: 12/16/2011
Posts: 368



just found your post asking to connect....how can I help?




email: jim_knox@charter.net

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