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Head device using electromagnetic waves
Does anyone know anything about this?
The open-label study was a single center, single arm trial in eight patients 63 years of age and older with mild to moderate Alzheimer’s disease (AD) to evaluate the safety and initial efficacy of Transcranial Electromagnetic Treatment (TEMT). Patients were enrolled at the University of South Florida Health/Byrd Alzheimer’s Institute, which also conducted most clinical study assessments. Treatment was administered in the patient’s home by a caregiver (spouse, relative), using the MemorEM device.
Patients received TEMT for one-hour periods twice daily for two months. Although limitations of this study include the small number of subjects, not having a control group, and being of relatively short treatment duration, 120 treatments were administered in-home and the cognitive benefits observed were clinically important/meaningful at the highest levels. Providing additional credibility to the observed cognitive enhancements were the beneficial changes in AD markers in blood and CSF, as well as the enhancement in brain MRI imaging.
A biotech commentator sent me this link to the study:
This one confounds me. Some electromagnetic stimulation may be good for the brain, but too much is not (the authors' claim that what they are using is safe and effective).
I don't see this holding up over the long-term, but I could certainly be wrong.
I've seen studies on TCDS TransCranial direct stimulation. Its being tried for Parkinsons, Tinnitus, I haven't really looked into it, here's a link.
Radiolab has an episode called 9 volt nirvana, I haven't heard it yet, but it sound interesting.
the tests also showed that their ADAS-cog score, which assesses their memory, thinking, judgment and other cognitive skills, was raised by 4 points or more in 7/8 patients.
This score is used as the gold standard for judging the efficacy of all AD treatments, and the four-point increase shows a large increase in cognitive performance which translates into clinically important improvement in mental function.
This is all the more satisfying when it is contrasted with the typical 4+ decline in this score over one year in patients with AD.
In other words, it could be interpreted as turning the clock back one whole year on the disease – a significant improvement in cognitive performance.
A bunch of other News stories about Dr Reheinhart's Experiment to "help synchronize electrical activity across brain areas.
8 Apr 2019 ... Electrical stimulation of the human brain can produce a striking improvement in the short-term memory of the elderly, with people in their 60s ...
8 Apr 2019 ... Low-level electrical stimulation can reverse some of the cognitive ... will set the stage for improving cognition in both healthy adults and ... older adults perform worse, on average, on working-memory tasks than younger adults.
8 Apr 2019 ... Study suggests out-of-sync brain waves help drive cognitive aging. ... generating electrical waves that let you hold information for as long as it is needed. .... transcranial stimulation has been shown to restore working memory ...
12 Apr 2019 ... Electrostimulation can improve working memory in people ... by using electrical currents to noninvasively stimulate brain areas that have lost ... However, when the older adults received 25 minutes of mild stimulation delivered ...
29 Apr 2019 ... Researchers at Boston University have shown that it is possible to improve memory in older folks by using electric stimulation.
10 Apr 2019 ... Electrostimulation of the brain could improve working memory of older ... The study demonstrated that electrical stimulation restores these ...
10 Jun 2019 ... All brain processes, including memory, rely on the transfer of information throughout the brain by electrical and chemical signals. Memory ...
8 Apr 2019 ... "We can bring back the superior working memory function you had ... of alternating current to improve working memory in older people. ... Other labs have also shown that electrical stimulation of the brain can improve memory.
10 May 2019 ... Mild electrical stimulation gives older adults the memory performance of 20-year olds.
8 Apr 2019 ... Working memory of older group temporarily improves to match younger group in ... After electrical stimulation, working memory in older adults ...
The Head of R & D for Biogen left to join a company called Apple Tree Partners(?). Gala Therapeutics, which is using RheOx uses a minimally invasive procedure to deliver non-thermal energy to the airways to reduce mucus-producing cells in patients with Chronic Bronchitis - If I remember it correctly Gala Therapeutics was created by Apple Tree Partners.
When will people realize that there is more to treatment than drugs, in fact, what if a cell could be influenced- the same way a drug would, but without the drug, with.... I don't know... some kind of .........magic energy that isn't light and isn't heat.
lets see ....if it can heal people by sending that energy into the cells, whether its intra-venously ( inside the vein), shining NIR light at the photoreceptors in the eyes, or into up the nasal passages. Perhaps a really far-reaching version of light could penetrate the skull itself.
Desperate people and research is starting to show that merely 'shining' light or energy at a cell can improve that cells functionality. (and this benefit travels throughout the body to wherever its needed.) Though it will probably still be faster to use light or red light or beyond red light - near the brain, rather than by aiming that energy up an AD sufferer's bottom, as someone once suggested.
I was reading a study on the effect of electromagnetic waves on the brain, researchers expected to see an increase in blood flow to specific areas of the brain. But the increase of blood flow itself was negligible, what they did see was that theta waves increased.
Much has been written about Gamma waves, this researcher suggested that Theta waves are the waves the brain uses to communicate within itself, these waves bring all the communication together in the way that creates meaning or understanding (awareness of the thought in a larger context.
I should probably break this down into a few topics, add and verify my research. For now, please take it with a large grain of salt.
Oh, and even though their R&D guy left for a partly bio-medical tech company, (people do like to move up in their careers, get more responsibility and better titles)
- I still have a strong suspicion that Biogen is onto something. With past critics saying they spend too much time trying to narrow a trial down to only the sub-group of people it can help - I wouldn't be surprised if they have found something that only works for people with a particular gene. Once they can identify who it would help, ta-daaa, you have genetically customized medicine. But this is purely my speculation.
And I will say it again, It should only be a matter or time; until scientist can separate the useful parts of the drug from the harmful parts, or modify the delivery to penetrate the BBB, while sparing the other organs.
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Sep 16, 2019, 07:00 ET
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MENLO PARK, Calif., Sept. 16, 2019 /PRNewswire/ -- Gala Therapeutics, Inc. (Gala), a developer of medical devices to treat pulmonary disease, announced the U.S. Food and Drug Administration (FDA) granted Breakthrough Device Designation (FDA) for the RheOxTM Bronchial RheoplastyTM system. RheOx uses a minimally invasive procedure to deliver non-thermal energy to the airways to reduce mucus-producing cells in patients with Chronic Bronchitis.
"Today there are no treatments to address the debilitating symptoms impacting the quality of life in patients with Chronic Bronchitis. We are excited by FDA's decision to designate RheOx as a breakthrough device, underscoring the significant unmet need for these patients," said Jonathan Waldstreicher, MD, CEO of Gala Therapeutics. "We look forward to working with FDA to bring a solution that improves the lives of these patients."
The Breakthrough Device Program is intended to streamline the regulatory pathway for first-of-its-kind medical devices that can provide more effective treatment for patients suffering from life-threatening or irreversibly debilitating diseases to ensure that patients have timely access to vital treatments.
Neuro-Degenerative & Keywords Pulsed Brain -Studies with Results
Note: Certain devices and references made herein to specific
indications of use may have not received clearance or approval by the
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Only in the UK
Transcranial Pulse Stimulation (TPS®) in Alzheimer’s Disease
Applied knowledge in neurology – The TPS® method of action
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3D camera with patient and handpiece position detection / Calibration probe and tracking glasses with markers / TPS® handpiece with markers
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K. et al.: Low-energy extracorporeal shock wave therapy for promotion
of vascular endothelial growth factor expression and angiogenesis and
improvement of locomotor and sensory functions after spinal cord injury,
J Neurosurg Spine, Vol. 25(6), Pages 745–755, 20164Hatanaka,
K. et al.: Molecular mechanisms of the angiogenic effects of low-energy
shock wave therapy: roles of mechanotransduction, Am J Physiol Cell
Physiol, Vol. 311(3), C378–C385, 20165Mariotto, S. et al.: Extracorporeal shock waves: From lithotripsy to anti-inflammatory action by NO production, Nitric Oxide, Vol. 12(2), 89–96, 20056d´Agostino,
M. C. et al.: Shock wave as biological therapeutic tool: From
mechanical stimulation to recovery and healing, through
mechanotransduction, Int J Surg., Dec. 24(Pt B), 147-153, 2015 7López-Marín, L. M. et al.: Shock wave–induced permeabilization of mammalian cells, Phys Life Rev., 26-27:1-38, 2018 8Wang,
B. et al.: Low-Intensity Extracorporeal Shock Wave Therapy Enhances
Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling
Pathway, Int J Mol Sci., Feb 16;18(2). pii: E433, 2017
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I just read that some flowers are buzz - pollinated. Its actually the hum produced by the bees (wings?) that triggers a reaction to release pollen from the plant.
Scientists have replicated pollen release with a tuning fork.