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I Have Alzheimer’s or Another Dementia
I have Pick's Disease
Certain antioxidants can be used to treat Alzheimer's disease, so I looked some information about using them for frontotemporal lobe dementia and found this:
Little solid evidence exists that antioxidants and other supplements help those with FTD. You and your family members should talk with your healthcare provider about whether to try antioxidants and other supplements, such as coenzyme Q10, vitamin E, vitamin C, and B vitamins to support brain health.
Feru-guard (a combination of ferulic acid in Angelica archangelica and rice bran oil) has shown some positive treatment effects, but it is not available in the United States. I am not sure if a ferulic acid supplement would produce similar effects.
Treatment with Feru-guard led to decreased scores on the Neuropsychiatric Inventory in 19 of 20 patients and significantly decreased the score overall. The treatment also led to significantly reduced subscale scores on the Neuropsychiatric Inventory ("delusions", "hallucinations", "agitation/aggression", "anxiety", "apathy/indifference", "irritability/lability" and "aberrant behavior"). There were no adverse effects or significant changes in physical findings or laboratory data.
I hope that you will be able to get some advice and insights from others on this site.
Welcome, lollyred. I'm sorry that you have received that diagnosis. I have similar difficulties although from a different cause. I am learning to compensate as much as I can. Do you have a support system?
Welcome to our world, lollred. I'm so sorry for your diagnosis, bur so glad you found us.
I'd suggest that yu get involved in Best PRACtICEs.
There is a lot of evidence that it slows down the progression of Alzheimers.
I don't know about Pick's, but the life style is good. if thus is a major change of life style, slowly is the word.
1. Meditteranean DIET. A LITTLE WINEM ESPECIALLY RED IS OK.
2. Physical exercise.
4.Socialization. Maintain or increase. Most of us do not like large grousm but smqall groups are fine.
5. Take meds if prscribed.
I was not aware of the following a week ago:
FTD [Frontotemporal Dementia] used to be called Pick's disease after Arnold Pick, a physician who in 1892 first described a patient with distinct symptoms affecting language. Some doctors still use the term "Pick's disease." Other terms you may see used to describe FTD include frontotemporal disorders, frontotemporal degenerations and frontal lobe disorders.
Frontotemporal dementia or FTD is a progressive disorder of the brain. It can affect behaviour, language skills and movement.
The main subtypes of FTD are called behavioural variant FTD and primary progressive aphasia or PPA.
PPA can be further split into two main subtypes, one of which is called semantic dementia or SD.
The first symptoms of SD are usually very subtle changes in finding words or understanding them. This is thought to be due to loss of semantic knowledge, our understanding of what things are or their meaning.
I am sorry for your diagnosis, too, lollyred. This is a great place to come for suggestions and comfort.
Many of the caregivers are caring for LOs with these types of dementias. You might include FTD, or aphasia in your search words.
Here are a couple of websites with good information.
Jo C. just posted an extensive history of her and her mother's experiences with getting a diagnosis on this thread.
Certainly, Michael. This is the most optimistic study that I have found so far regarding the treatment of frontotemporal dementia (perhaps too optimistic).
This is a bit technical, but quite interesting.
mTOR inhibition is beneficial in neurodegenerative disease models and its effects are often attributable to the modulation of autophagy [removal of damaged or harmful proteins, for instance] and anti-apoptosis [preventing cell death]. Here, we report a neglected but important bioenergetic effect of mTOR inhibition in neurons. mTOR inhibition by rapamycin significantly preserves neuronal ATP levels [energy for cells]
Ferulic acid (FA), a naturally occurring polyphenol abundant in vegetables and rice bran, is known to possess a potent antioxidant activity, thereby protecting cells from oxidative stress...These results indicate that ferulic acid is almost the equivalent of rapamycin in the ability to inhibit mTor (TORC1), which makes it a potent activator of basal autophagy.
Ferulic acid does seem to help with behavioral problems in frontotemporal dementia, perhaps it helps with semantic issues as well. I am not sure if the combination of ferulic acid with rapamycin would provide additional benefits or alternatively would be of harm. Maybe a doctor trained in frontotemporal dementia would know the answer.
Because the condition Dr. Pick studied in the 1890's is now so much better understood, and it's variations have been categorized, it now is named for the areas of the brain it affects; the frontal & temporal lobes. FTD stands for Fronto-Temporal Degeneration. Although over 70% of cases are the behavioral variant (FTDbv), 10-15% are of the speech variant, Primary Progressive Aphasia (PPA). Up until 2011, two variants were recognized, but there are now three: Semantic, Non-fluent Anti-Grammatic, and Logopenic. Several other rare types complete the FTD umbrella of variants.
There have been many discussions on the main forums if you search using "FTD" or "Fronto-Temporal." These threads include many links for more info & support. "What If It's Not Alzheimer's" Ed. by G.& L. Radin is a good reference.