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Head device using electromagnetic waves
Keep It 100
Posted: Thursday, September 19, 2019 10:31 AM
Joined: 2/26/2017
Posts: 585

Does anyone know anything about this?

The open-label study was a single center, single arm trial in eight patients 63 years of age and older with mild to moderate Alzheimer’s disease (AD) to evaluate the safety and initial efficacy of Transcranial Electromagnetic Treatment (TEMT). Patients were enrolled at the University of South Florida Health/Byrd Alzheimer’s Institute, which also conducted most clinical study assessments. Treatment was administered in the patient’s home by a caregiver (spouse, relative), using the MemorEM device.

Patients received TEMT for one-hour periods twice daily for two months. Although limitations of this study include the small number of subjects, not having a control group, and being of relatively short treatment duration, 120 treatments were administered in-home and the cognitive benefits observed were clinically important/meaningful at the highest levels. Providing additional credibility to the observed cognitive enhancements were the beneficial changes in AD markers in blood and CSF, as well as the enhancement in brain MRI imaging.

Lane Simonian
Posted: Thursday, September 19, 2019 10:45 AM
Joined: 12/12/2011
Posts: 5085

A biotech commentator sent me this link to the study:

This one confounds me.  Some electromagnetic stimulation may be good for the brain, but too much is not (the authors' claim that what they are using is safe and effective).

I don't see this holding up over the long-term, but I could certainly be wrong.

Posted: Thursday, September 19, 2019 11:10 AM
Joined: 2/17/2019
Posts: 380

I've seen studies on TCDS TransCranial direct stimulation. Its being tried for Parkinsons, Tinnitus, I haven't really looked into it, here's a link.

Radiolab has an episode called 9 volt nirvana, I haven't heard it yet, but it sound interesting.


Posted: Thursday, September 19, 2019 11:52 PM
Joined: 2/17/2019
Posts: 380

the tests also showed that their ADAS-cog score, which assesses their memory, thinking, judgment and other cognitive skills, was raised by 4 points or more in 7/8 patients.

 This score is used as the gold standard for judging the efficacy of all AD treatments, and the four-point increase shows a large increase in cognitive performance which translates into clinically important improvement in mental function.

This is all the more satisfying when it is contrasted with the typical 4+ decline in this score over one year in patients with AD. 

In other words, it could be interpreted as turning the clock back one whole year on the disease – a significant improvement in cognitive performance.

Posted: Thursday, November 21, 2019 12:09 PM
Joined: 2/17/2019
Posts: 380

  A bunch of other News stories about Dr Reheinhart's Experiment to "help synchronize electrical activity across brain areas.

8 Apr 2019 ... Electrical stimulation of the human brain can produce a striking improvement in the short-term memory of the elderly, with people in their 60s ...

8 Apr 2019 ... Low-level electrical stimulation can reverse some of the cognitive ... will set the stage for improving cognition in both healthy adults and ... older adults perform worse, on average, on working-memory tasks than younger adults.

8 Apr 2019 ... Study suggests out-of-sync brain waves help drive cognitive aging. ... generating electrical waves that let you hold information for as long as it is needed. .... transcranial stimulation has been shown to restore working memory ...

Electrostimulation can improve working memory in people: As ...

12 Apr 2019 ... Electrostimulation can improve working memory in people ... by using electrical currents to noninvasively stimulate brain areas that have lost ... However, when the older adults received 25 minutes of mild stimulation delivered ...

Electric Stimulation Improves the Working Memory of Older People

29 Apr 2019 ... Researchers at Boston University have shown that it is possible to improve memory in older folks by using electric stimulation.

Electrostimulation could boost memory in elderly people

10 Apr 2019 ... Electrostimulation of the brain could improve working memory of older ... The study demonstrated that electrical stimulation restores these ...

Brain Stimulation May Improve Memory in Elderly Individuals ...

10 Jun 2019 ... All brain processes, including memory, rely on the transfer of information throughout the brain by electrical and chemical signals. Memory ...

Zapping brain with precise electrical current boosts working memory ...

8 Apr 2019 ... "We can bring back the superior working memory function you had ... of alternating current to improve working memory in older people. ... Other labs have also shown that electrical stimulation of the brain can improve memory.


8 Apr 2019 ... Working memory of older group temporarily improves to match younger group in ... After electrical stimulation, working memory in older adults ... 

Posted: Friday, November 22, 2019 11:56 AM
Joined: 2/17/2019
Posts: 380

T He


The Head of  R & D for Biogen left to join a company called Apple Tree Partners(?). Gala Therapeutics, which is using RheOx uses a minimally invasive procedure to deliver non-thermal energy to the airways to reduce mucus-producing cells in patients with Chronic Bronchitis - If I remember it correctly Gala Therapeutics was created by Apple Tree Partners.

 When will people realize that there is more to treatment than drugs, in fact, what if a cell could be influenced- the same way a drug would, but without the drug, with.... I don't know... some kind of .........magic energy that isn't light and isn't heat.

lets see ....if it can heal people by sending that energy into the cells, whether its intra-venously ( inside the vein), shining NIR light at the photoreceptors in the eyes, or into up the nasal passages. Perhaps a really far-reaching version of light could penetrate the skull itself.

Desperate people and research is starting to show that merely 'shining' light or energy at a cell can improve that cells functionality. (and this benefit travels throughout the body to wherever its needed.) Though it will probably still be faster to use light or red light or beyond red light - near the brain, rather than by aiming that energy up an AD sufferer's bottom, as someone once suggested.

I was reading a study on the effect of electromagnetic waves on the brain, researchers expected to see an increase in blood flow to specific areas of the brain. But the increase of blood flow itself was negligible, what they did see was that theta waves increased.

Much has been written about Gamma waves, this researcher suggested that Theta waves are the waves the brain uses to communicate within itself, these waves bring all the communication together in the way that creates meaning or understanding (awareness of the thought in a larger context.

I should probably break this down into a few topics, add and verify my research. For now, please take it with a large grain of salt.


Oh, and even though their R&D guy left for a partly bio-medical tech company, (people do like to move up in their careers, get more responsibility and better titles)

 - I still have a strong suspicion that Biogen is onto something. With past critics saying they spend too much time trying to narrow a trial down to only the sub-group of people it can help - I wouldn't be surprised if they have found something that only works for people with a particular gene.  Once they can identify who it would help, ta-daaa, you have genetically customized medicine. But this is purely my speculation.


And I will say it again, It should only be a matter or time; until scientist can separate the useful parts of the drug from the harmful parts, or modify the delivery to penetrate the BBB, while sparing the other organs.

Rant Over.



 Gala Therapeutics Receives FDA Breakthrough Device Designation for the Minimally Invasive RheOx™ System for Chronic Bronchitis





Gala Therapeutics, Inc. 

Sep 16, 2019, 07:00 ET


MENLO PARK, Calif.Sept. 16, 2019 /PRNewswire/ -- Gala Therapeutics, Inc. (Gala), a developer of medical devices to treat pulmonary disease, announced the U.S. Food and Drug Administration (FDA) granted Breakthrough Device Designation (FDA) for the RheOxTM Bronchial RheoplastyTM system. RheOx uses a minimally invasive procedure to deliver non-thermal energy to the airways to reduce mucus-producing cells in patients with Chronic Bronchitis.

"Today there are no treatments to address the debilitating symptoms impacting the quality of life in patients with Chronic Bronchitis. We are excited by FDA's decision to designate RheOx as a breakthrough device, underscoring the significant unmet need for these patients," said Jonathan Waldstreicher, MD, CEO of Gala Therapeutics. "We look forward to working with FDA to bring a solution that improves the lives of these patients."

The Breakthrough Device Program is intended to streamline the regulatory pathway for first-of-its-kind medical devices that can provide more effective treatment for patients suffering from life-threatening or irreversibly debilitating diseases to ensure that patients have timely access to vital treatments. 

Lane Simonian
Posted: Friday, November 22, 2019 1:31 PM
Joined: 12/12/2011
Posts: 5085

It always amazes me how much information regarding potentially effective treatments for  Alzheimer's disease either get ignored or are summarily dismissed.    I blame this in part on how various pharmaceutical companies, research scientists, funding organizations, etc. want so desparately to treat this disease with a drug.
Posted: Sunday, November 24, 2019 8:29 PM
Joined: 2/17/2019
Posts: 380

Neuro-Degenerative & Keywords Pulsed Brain -Studies with Results


9 Recruiting Brain Stimulation for Neurological Patients
  • Alzheimer Disease
  • Device: NEUROLITH
  • Medical University of Vienna
    Vienna, Austria

 Vienna,  Austria

Posted: Sunday, November 24, 2019 8:30 PM
Joined: 2/17/2019
Posts: 380

Note: Certain devices and references made herein to specific indications of use may have not received clearance or approval by the United States Food and Drug Administration. Practitioners in the United States should first consult with their local STORZ MEDICAL representative in order to ascertain product availability and specific labeling claims. Federal (USA) law restricts certain devices referenced herein to sale, distribution, and use by, or on the order of a physician, dentist, veterinarian, or other practitioner licensed by the law of the State in which she/he practices to use or order the use of the device.

 Only in the UK


Transcranial Pulse Stimulation (TPS®) in Alzheimer’s Disease

Product video MASTERPUL ONE

Applied knowledge in neurology – The TPS® method of action

The key mechanism induced by TPS® is mechanotransduction. The stimulation of growth factors, primarily VEGF3,4, not only improves cerebral blood flow, but also promotes the formation of new blood vessels (angiogenesis) and nerve regeneration. An additional effect is the release of nitric oxide (NO)5, which leads to direct vasodilation and improved blood circulation.TPS® enables targeted stimulation of cerebral regions.

TPS® enables targeted stimulation of cerebral regions.

Biological effects of TPS®

  • Mechanotransduction6
  • Increase in cell permeability7
  • Stimulation of mechanosensitive ion channels6
  • Release of nitric oxide (NO)5, which leads to vasodilation, increased metabolic activity and angiogenesis and has an anti-inflammatory effect
  • Stimulation of vascular growth factors (VEGF)3,4
  • Stimulation of BDNF8
  • Migration and differentiation of stem cells4,6

TPS® can stimulate deep cerebral regions, reaching as much as 8 cm into the brain. Owing to the short duration of the TPS® stimulation, tissue heating is avoided. The pulses applied to the treatment area thus develop their maximum clinical effectiveness. TPS® treatment is performed through the closed skull. The patient is not immobilized during the treatment and able to move freely. TPS® treatment has been shown to significantly improve CERAD test performance and to reduce Beck’s depression index in patients with mild to moderate dementia. Over 1500 treatments have already been performed using the NEUROLITH® system.

Advantages of TPS®

  • 6 treatment sessions in 2 weeks
  • Outpatient treatment (30 minutes/session)
  • Painless and without side effects
  • Personalized treatment based on MRI data
  • Adjuvant cognitive training not required
  • Shaving of the scalp not required
  • No immobilization of the patient during treatment

BodyTrack® – Treatment documentation in real time

Real-time tracking of the handpiece position enables automatic visualization of the treated regions. The use of personalized MRI data allows specific characteristics of the patient’s brain to be taken into account. Every time the handpiece position changes, the visualization of the target regions in the loaded MRI scans is automatically updated. The energy applied is highlighted in colour. The BodyTrack® software is a unique tool for the visualization and control of the TPS® pulses applied and of treatment progress.

Real-time visualization of TPS® treatmentReal-time visualization of TPS® treatment

Advantages of the BodyTrack® software

  • Use of personalized MRI data
  • Visualization of MRI data in 3 planes (axial, coronal, sagittal)
  • Coloured visualization of the treatment region
  • Real-time visualization of TPS® pulse distribution
  • Continuous visualization and documentation of the energy applied and of treatment progress

NEUROLITH® – The perfect solution to facilitate Alzheimer’s treatment

NEUROLITH® – an innovative system with convincing design features! The special ergonomic shape of the TPS® handpiece minimizes hand fatigue to facilitate treatment working directly on the patient. The coupling surface adapts easily to any shape of head, making the treatment with focused pulses simple and efficient. The NEUROLITH® software includes patient management functionalities with retrievable data and recommended treatment parameters.

Transcranial Pulse Stimulation (TPS®) in Alzheimer’s Disease3D camera with patient and handpiece position detection / Calibration probe and tracking glasses with markers / TPS® handpiece with markers

Advantages of the NEUROLITH®

  • Focused stimulation of deep cerebral regions
  • Personalized 3D visualization of patient’s head
  • 3D infrared camera system for precise cerebral tracking
  • USB interface for MRI data import
  • Patient database

3Yahata, K. et al.: Low-energy extracorporeal shock wave therapy for promotion of vascular endothelial growth factor expression and angiogenesis and improvement of locomotor and sensory functions after spinal cord injury, J Neurosurg Spine, Vol. 25(6), Pages 745–755, 2016
4Hatanaka, K. et al.: Molecular mechanisms of the angiogenic effects of low-energy shock wave therapy: roles of mechanotransduction, Am J Physiol Cell Physiol, Vol. 311(3), C378–C385, 2016
5Mariotto, S. et al.: Extracorporeal shock waves: From lithotripsy to anti-inflammatory
action by NO production, Nitric Oxide, Vol. 12(2), 89–96, 2005
6d´Agostino, M. C. et al.: Shock wave as biological therapeutic tool: From mechanical stimulation to recovery and healing, through mechanotransduction, Int J Surg., Dec. 24(Pt B), 147-153, 2015
7López-Marín, L. M. et al.: Shock wave–induced permeabilization of mammalian cells, Phys Life Rev., 26-27:1-38, 2018
8Wang, B. et al.: Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway, Int J Mol Sci., Feb 16;18(2). pii: E433, 2017

Lohstampfestrasse 8 8274 Tägerwilen
Switzerland Tel.: +41 (0)71 677 45 45
Fax: +41 (0)71 677 45 05  

Posted: Sunday, December 15, 2019 6:42 PM
Joined: 2/17/2019
Posts: 380


How Our Non-Invasive Electroceutical® Therapies Work:

Pulsed Electromagnetic Field-based (PEMF) Electroceuticals® which use a changing electromagnetic field to deliver electrical stimulation to tissues via induction function by accelerating the production of the endogenous constitutive nitric oxide synthesis systems (cNOS or eNOS): the anti-inflammatory system.

Nitric oxide (NO) is an essential molecule involved in several physiological and pathological processes within the mammalian body. NO is synthesized by nitric oxide synthase (NOS) which oxidizes a guanidine nitrogen of L-arginine releasing nitric oxide in the form of a free radical and citrulline.

Three isoforms of the NOS have been identified: endothelial (eNOS or NOS-3), neuronal (nNOS or NOS-1), and inducible (iNOS or NOS-2) – each with separate functions. The neuronal enzyme (NOS-1) and the endothelial isoform (NOS-3) are calcium-dependent and produce low levels of gas as a cell signaling molecule. The inducible isoform (NOS-2) is calcium independent and produces large amounts of gas which can be cytotoxic.

Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti-tumor and anti-pathogenic activities. Sufficient levels of NO production are necessary in protecting an organ such as the heart, brain, or liver from ischemic damage. NO dilates blood vessels, raising blood supply and lowering blood pressure. Nitric Oxide is also an immune effector, producing an anti-inflammatory effect at physiological levels.

In 1992, for its importance in neuroscience, physiology, and immunology, nitric oxide was proclaimed the “Molecule of the Year”. The 1998 Nobel Prize in Physiology or Medicine was awarded for discovering nitric oxide’s role as a cardiovascular signalling molecule. Over a century after their medical introduction, the organic-nitrate pharmaceuticals, including nitroglycerine and amyl nitrite, were identified as precursors of nitric oxide.

FDA Cleared Medical Device...
clinically proven to significantly speed the healing process and reduce the need for pain medications

Posted: Sunday, December 15, 2019 6:45 PM
Joined: 2/17/2019
Posts: 380

SofPulse® Electroceutical™ Therapy

SofPulse® uses targeted microcurrents to transmit gentle pulses to the tissue to help reduce swelling and speed up the natural recovery process. The low levels of microcurrent are completely safe and in fact, are 1000 times lower than those emitted by a mobile phone.

Treatment with SofPulse allows you to better manage pain without the adverse side effects of narcotics and anti-inflammatory medication.  SofPulse reduces edema, the resulting pain level and thereby decreases the requirement for medication.  With less pain and less medication, you can move around sooner, which stimulates the body’s natural response to healing. For more information please visit:

[SofPulse® Electroceutical™ Therapy]

Posted: Monday, January 13, 2020 11:58 AM
Joined: 2/17/2019
Posts: 380

The worse the memory of the older people in Reinhart’s study, the more that alternating-current stimulation improved it. But even in younger adults with good memory, “we are seeing boosts in brain and behavior measures,” he said about unpublished results. “I think it is possible to turbocharge” their memory, too.
Posted: Tuesday, January 14, 2020 4:59 AM
Joined: 1/25/2018
Posts: 751

TEMT has been around for a few years for drug resistant depression with fair results. When research first started showing positive results with Alzheimer's patients insurers became concerned people with AD would start using it for their "depression" when in reality it was being used to treat their dementia.  My current insurer and my previous insurer both approve TEMT for treatment of depression UNLESS there is a concurrent Alzheimer's diagnosis. Then TEMT is denied categorically. You see, we can't be spending money on a safe, effective, drug free,  non-invasive treatment that may be able to treat two disabling health problems at once. No-No-No- we need to make sure the cost is pushed off on the formulary (medication) portion of the insurance. They can then control costs by refusing to cover all those expensive drugs.
Posted: Tuesday, January 21, 2020 11:41 AM
Joined: 2/17/2019
Posts: 380

Oh for crying out loud!
Posted: Saturday, January 25, 2020 11:10 PM
Joined: 10/24/2019
Posts: 746

My DW’s neuro uses magnetic brain stimulation in a clinical setting, for two objectives:  improved short term memory, and preserving/delaying progression of verbal fluency.
Posted: Sunday, February 9, 2020 1:04 PM
Joined: 2/17/2019
Posts: 380

Really, would you send me that Dr.s Name, location of practice?
Posted: Sunday, March 8, 2020 2:43 PM
Joined: 2/17/2019
Posts: 380

I just read that some flowers are buzz - pollinated. Its actually the hum produced by the bees (wings?) that triggers a reaction to release pollen from the plant.

Scientists have replicated pollen release with a tuning fork. 

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